Lockdown

With the highest homicide rate in the nation, the streets of Detroit are rampant with violent crimes, drug abuse and prostitution. But at the citys Wayne County Jail, female offenders are offered one last chance to clean up their lives.

At Colorado's innovative Youthful Offender System, violent juvenile felons are given a last chance at a crime-free life before going to adult prisons. But if they fail, hard time could mean sexual abuse or risk of suicide.

Maryland's only female prison holds women from petty dealers to cold-blooded killers. Each with their own story, a young lifer, a mother-to-be, and a recovering crack addict illustrate the challenges of women behind bars.

The newest and largest prison in Colorado is home to more than 2,000 killers, kidnappers and drug dealers. Here the warden and his team must control some of the toughest and most aggressive offenders and even work to turn them around.

At St. Louis County Jail tensions could erupt at any moment, but for each unit of 67 inmates, there's just one corrections officer - armed with nothing but a panic button and pepper spray - to keep all hell from breaking loose.

Just a few miles south of the U.S. border lies one of Mexico's most notorious penitentiaries. Meet Rogelio, a suspected gang member; Raul and Rosi, who fell in love behind bars; and Vincent, an American in solitary for his own protection.

Lockdown goes behind the razor wire for an in-depth look at Cleaveland's Cuyahoga County Jail. See the drama unfold as the Special Response Team faces a new gang that preys on other inmates.