After suffering a personal tragedy, Bryan Mills embarks on a vengeful mission to bring down a ruthless cartel boss.

Sidelined for weeks, Bryan finally gets an opportunity to work in the field. The ensuing mission unearths a sinister conspiracy surrounding a government official’s death. Meanwhile, Hart makes contact with a man from her past.

Bryan and team search for a suspected terrorist who has been taken, leading them to uncover a deeper plot within their own government. Christina receives troubling news and turns to Harry for support. Asha expresses her concern over Bryan's fixation with Mejia.

Riley's insistence to uncover the truth behind a fatal drug given to war vets results in her asset's child being taken.

Christina (Jennifer Beals) orders the retrieval of sensitive documents in Zurich needed to prevent economic and political disaster.

The ODNI is asked to facilitate the defection of a Russian FSB agent, but the agent's pregnant girlfriend throws a curve in the team's plans.

During the team's efforts to thwart a Mejia weapons operation, Bryan (Clive Standen) is taken. As he relies on his ODNI training to survive, the team attempts a daring rescue.

The ODNI assists an Israeli spy with early onset Alzheimer's, whose own agency is out to kill her.

The ODNI is forced to deliver Mejia (guest star Romano Ozari) to the FBI but catch wind of the cartel's plans to hijack the transfer.

As the FBI threatens to remove Christina (Jennifer Beals) from command, Bryan (Clive Standen) and John (Gaius Charles) lead a rogue mission to stop Mejia's associates before they cross the border.