In the season premiere, the Gallaghers adjust to life in the pandemic, while Frank (WILLIAM H. MACY) fears the loss of the Southside to gentrification, and Deb becomes her own boss.

Lip’s home renovations run him into some trouble with his new neighbors, while Carl’s first day on the force is not the Dirty Harry fantasy he thought it would be.

Debbie (EMMA KENNEY) loses track of Franny and has to balance her search with her job, but Frank and Franny have a day of weed runs and adventure. Carl gets a new Training Officer.

When the Milkoviches move in next door and wreak havoc, Frank, Kev & Liam plot how to get rid of them. Meanwhile, Mickey (NOEL FISHER) works a security gig for Kev & V.

While Ian and Mickey get creative when the safety of their security gig is questioned, Lip and Tami get surprising news about their house that forces them to look elsewhere.

While Frank’s day takes some unexpected turns and Liam deals with inner turmoil after doing a bad thing, Lip is forced to figure out a plan for the future.

While Lip and Brad prepare to sell stolen bikes, Kevin has to think quickly when spotted on a stolen chopper. Then, Debbie and Sandy have another visitor from Sandy’s past.

Veronica is depressed about her mom moving so Kevin tries to cheer her up, while planning a special surprise. Carl is put on Vice Squad which is all fun and games… until it’s not.

While Mickey and Ian learn a surprising truth about Terry’s past, Liam tries to find a new place to live. And Frank wants to pull one last heist with the old gang.

While Carl’s disillusionment with the police force comes to a head, Lip has a million projects going on – and Frank is one of them. Then, Debbie hunts for a new place.

While Lip has some promising leads on the sale of the house, Ian & Mickey try to adjust to life on the West Side. And Liam reminds Frank what makes him Frank.

In the series finale, Frank faces his mortality, Kev and V try to sell the Alibi, Lip gets a new job, Carl finds his purpose, Debbie meets someone, and Ian and Mickey go shopping.