Lea and Shaun's new relationship will become tested. Park gets ready to move back to Phoenix. Morgan puts herself and several members of the staff in danger. Claire continues to work through her grief from the death of Melendez.

Shaun has a hard time balancing his fears and concerns about potentially jeopardizing Lea's health and wanting to be with the woman he loves. Claire looks for a way to grieve Melendez's death. Park and Mia discuss their future together.

With several candidates vying for residency at St. Bonaventure, Lim tasks Shaun, Claire and Alex with mentoring the top first-year resident contenders; Shaun inadvertently insults Lea while discussing the pros and cons of a controversial surgery.

Morgan and Shaun's pregnant patient with twins has pain, forcing the doctors to grapple with a decision no one wants to make; Shaun asks Lea to move back in despite her reservations.

Dr. Murphy questions his decision to give the new residents autonomy when an intern's misdiagnosis has dire consequences; a patient has a ruptured cyst affecting key functions of her brain; Dr. Morgan Reznick and Park bond over failed relationships.

Dr. Audrey Lim struggles to cope with the residual emotional trauma of COVID-19; Dr. Claire Browne suggests a radical treatment to help a war veteran who has PTSD; Dr. Shaun Murphy declares he doesn't want to teach the new residents any more.

Dr. Morgan Reznick discovers her patient's wealth and obsession with extending his life is a dangerous mix that could end up costing more than he can afford.

The team treats a teenage gymnast who experiences complications from her intensive training. Shaun meets Lea's parents for the first time.

Lim is challenged by the unique circumstances surrounding a pregnant patient with an aggressive tumor. Elsewhere, after misdiagnosing a patient, Claire makes a disconcerting discovery about certain practices at the hospital.

When the hospital is hit with a cyberattack threatening to shut down life-saving machines, Lea rises to the challenge and looks to outsmart the hackers to prove herself. Meanwhile, the team treats an inspirational cancer survivor-turned-successful-philanthropist who harbors a dark secret.

After bringing in an incredibly unique and complicated spinal surgery, Dr. Aaron Glassman challenges the residents for an opportunity to join him in the operating room. Meanwhile, Shaun and Morgan disagree on how to treat a comatose patient with a cancerous tumor.

When a renowned surgeon comes to St. Bonaventure for treatment, the team's enthusiasm is quickly overshadowed by the doctor's behavior. After studying his case, Dr. Shaun Murphy sees a pattern he recognizes. Meanwhile, Shaun and Lea are forced to make a life-changing decision that will alter the course of their relationship.

Claire is blindsided when her absentee father shows up at her door. Meanwhile, Shaun feels disconnected from Lea, causing tension in their relationship.

After finding out the gender of their unborn child, Lea's enthusiasm prompts Shaun to make an effort to be a more supportive partner. Meanwhile, the team treats a navy pilot whose previous doctor's misdiagnosis compromises her chances at a full recovery.

After a political protest turns violent, the team races to save two young gunshot victims.

Shaun struggles with his role as Lea's partner after complications arise with the pregnancy and his instincts as a medical professional kick in. Meanwhile, Dr. Park, Dr. Andrews and Asher disagree on how to address an elderly patient's wishes.

Dr. Claire Brown and the team must face hard truths about what lines they are willing to cross when one of Claire's idols becomes her patient.

Shaun and Lea go on a camping trip to distract themselves from their grief over their miscarriage; Morgan and Park argue about the best course of treatment for their patient.

The team travels to Guatemala on a mission to help patients at a rural hospital; the team faces a small community that is in desperate need of help, but they must identify who they can help most; Lea is still struggling with the loss of her baby.

Dr. Shaun Murphy must perform a risky surgery on a patient without electricity when the power suddenly goes out; Dr. Lim and Dr. Mateo Rendón Osma's relationship deepens as they overcome difficulties during their surgery.